BOTOX® Injections A million people have been treated with BOTOX® Cosmetic since its FDA approval in 2002. BOTOX® Cosmetic is the only FDA-approved treatment for the temporary reduction of moderate to severe frown lines between the brows in patients 18 to 65 years of age. What causes frown lines between the brows? The are two muscles largely responsible for frown lines between the brows. When those muscles contract, they draw the brows together. As skin becomes less elastic over time, repeated frowning can result in those moderate to severe lines between your brows. BOTOX® Cosmetic works by blocking nerve impulses, which reduces the movement of those muscles. With less movement, the skin surface gradually smoothes out, and the moderate to severe frown lines between your brows begin to fade. What is the treatment like? Your doctor will determine exactly where to administer the injections to achieve the best results. No anesthesia is required, although he or she may choose to numb the area with a cold pack or anesthetic cream prior to injecting. The entire procedure takes approximately ten minutes. Discomfort is minimal and brief- most patients compare the sensation to a bug bite. You may resume normal activity immediately. How soon will I see a difference? What kind of results can I expect? Visible results can last up to four months. After that, you may be ready to return for a follow-up treatment. Cialis 60mg online as reported here discount tadalafil online; taking tadalafil and sildenafil together visit this site erectile dysfunction age 45. Sildenafil vs levitra important source does tadalafil make urine smell, erectile dysfunction injections visit headache after taking cialis. 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